Difference between revisions of "20.109(S24):Class data"

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Revision as of 21:45, 29 February 2024

20.109(S24): Laboratory Fundamentals of Biological Engineering

Sp24 banner image.png

Spring 2024 schedule        FYI        Assignments        Homework        Class data        Communication        Accessibility

       M1: Drug discovery        M2: Protein engineering        M3: Project design       


Module 1: Drug discovery

Please find uploaded data for Mod 1 in the Dropbox folder linked here.


Please find the SMM screen results here.


DSF results:

Replicate #1 Replicate #2 Replicate #3 Average Tm
TR Orange
DMSO
Small molecule #1
Small molecule #6
Small molecule #9
Small molecule #10
TR Yellow
DMSO 48.12 47.61 49.13 48.29
Small molecule #2 48.62 46.59 44.55 46.59
Small molecule #10 47.61 47.61 47.61 47.61
Small molecule #11 44.5 45.6 44.5 44.9
Small molecule #13 47.1 47.1 49.1 47.8
TR Green
DMSO 43.02 45.06 45.06 44.37
Small molecule #2 43.02 47.10 45.57 45.23
Small molecule #6 46.08 49.65 46.08 47.27
Small molecule #9 44.04 45.06 46.59 45.23
Small molecule #10 46.08 45.57 48.62 46.76
TR Blue
DMSO 47.11149606 45.07968504 44.06377953 45.41832021
Small molecule #1 48.63535433 48.63535433 44.06377953 47.11149606
Small molecule #2 46.60354331 47.11149606 43.55582677 45.75695538
Small molecule #4 46.60354331 44.57173228 43.55582677 44.91036745
Small molecule #10 47.61944882 44.57173228 44.06377953 45.41832021
TR Pink
DMSO 47.1114961 66.9216535 81.6522835 65.2284777
Small molecule #1 36.444482 65.905748 66.4137008 56.2546457
Small molecule #2 45.5876378 82.668189 47.6194488 58.6250919
Small molecule #10 47.1114961 84.1920472 82.1602362 71.1545932
Small molecule #11 45.079685 82.160362 81.6522835 69.6307349


Replicate #1 Replicate #2 Replicate #3 Average Tm
WF Red
DMSO
Small molecule #3
Small molecule #4
Small molecule #5
Small molecule #8
WF Orange
DMSO
Small molecule #1
Small molecule #2
Small molecule #10
Small molecule #13
WF Yellow
DMSO
Small molecule #2
Small molecule #10
Small molecule #11
Small molecule #13
WF Green
DMSO
Small molecule #2
Small molecule #9
Small molecule #10
Small molecule #13
WF Blue
DMSO
Small molecule #5
Small molecule #9
Small molecule #10
Small molecule #13
WF Pink
DMSO
Small molecule #5
Small molecule #9
Small molecule #10
Small molecule #13
WF Purple
DMSO
Small molecule #5
Small molecule #9
Small molecule #10
Small molecule #13
WF Teal
DMSO
Small molecule #1
Small molecule #2
Small molecule #10
Small molecule #11

Module 2: Protein engineering

Please find uploaded data for Mod 2 in the Dropbox folder linked here.
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