Difference between revisions of "20.109(S24):Class data"
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Noreen Lyell (Talk | contribs) (→Module 1: Drug discovery) |
Noreen Lyell (Talk | contribs) (→Module 1: Drug discovery) |
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Please find the SMM screen results [[Media:Screen results.csv | here]]. | Please find the SMM screen results [[Media:Screen results.csv | here]]. | ||
+ | |||
'''DSF results:''' | '''DSF results:''' | ||
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| Replicate #3 | | Replicate #3 | ||
| Average T<sub>m</sub> | | Average T<sub>m</sub> | ||
+ | |- | ||
+ | | '''TR Orange''' | ||
+ | |- | ||
+ | | DMSO | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | |- | ||
+ | | Small molecule #1 | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | |- | ||
+ | | Small molecule #2 | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | |- | ||
+ | | Small molecule #3 | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | |- | ||
+ | | Small molecule #4 | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
|- | |- | ||
| '''TR Yellow''' | | '''TR Yellow''' | ||
|- | |- | ||
| DMSO | | DMSO | ||
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
|- | |- | ||
| Small molecule #1 | | Small molecule #1 | ||
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
+ | |- | ||
+ | | Small molecule #2 | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | |- | ||
+ | | Small molecule #3 | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | |- | ||
+ | | Small molecule #4 | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
|- | |- | ||
| '''TR Green''' | | '''TR Green''' | ||
|- | |- | ||
− | | | + | | DMSO |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
|- | |- | ||
− | | | + | | Small molecule #1 |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | |- |
− | | | + | | Small molecule #2 |
− | | | + | | |
− | | | + | | |
− | | | + | | |
+ | | | ||
+ | |- | ||
+ | | Small molecule #3 | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | |- | ||
+ | | Small molecule #4 | ||
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
|- | |- | ||
| '''TR Blue''' | | '''TR Blue''' | ||
|- | |- | ||
− | | | + | | DMSO |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
|- | |- | ||
− | | | + | | Small molecule #1 |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
|- | |- | ||
− | | | + | | Small molecule #2 |
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
|- | |- | ||
− | | | + | | Small molecule #3 |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
|- | |- | ||
− | | | + | | Small molecule #4 |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
|- | |- | ||
− | | ''' | + | | '''TR Pink''' |
|- | |- | ||
− | | | + | | DMSO |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
|- | |- | ||
− | | | + | | Small molecule #1 |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
|- | |- | ||
− | | | + | | Small molecule #2 |
+ | | | ||
+ | | | ||
+ | | | ||
+ | | | ||
|- | |- | ||
− | | | + | | Small molecule #3 |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
|- | |- | ||
− | | | + | | Small molecule #4 |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | | | + | | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
|- | |- | ||
|} | |} |
Revision as of 19:07, 29 February 2024
Module 1: Drug discovery
Please find uploaded data for Mod 1 in the Dropbox folder linked [here].
Please find the SMM screen results here.
DSF results:
Replicate #1 | Replicate #2 | Replicate #3 | Average Tm | |
TR Orange | ||||
DMSO | ||||
Small molecule #1 | ||||
Small molecule #2 | ||||
Small molecule #3 | ||||
Small molecule #4 | ||||
TR Yellow | ||||
DMSO | ||||
Small molecule #1 | ||||
Small molecule #2 | ||||
Small molecule #3 | ||||
Small molecule #4 | ||||
TR Green | ||||
DMSO | ||||
Small molecule #1 | ||||
Small molecule #2 | ||||
Small molecule #3 | ||||
Small molecule #4 | ||||
TR Blue | ||||
DMSO | ||||
Small molecule #1 | ||||
Small molecule #2 | ||||
Small molecule #3 | ||||
Small molecule #4 | ||||
TR Pink | ||||
DMSO | ||||
Small molecule #1 | ||||
Small molecule #2 | ||||
Small molecule #3 | ||||
Small molecule #4 |