Difference between revisions of "20.109(S24):Class data"
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− | [[Media:Screen results.csv | | + | Please find the SMM screen results [[Media:Screen results.csv | here]]. |
+ | |||
+ | '''DSF results:''' | ||
+ | |||
+ | <center> | ||
+ | {| border="1" | ||
+ | |- | ||
+ | | | ||
+ | | DMSO | ||
+ | | Small molecule | ||
+ | | '''12.5 μM''' | ||
+ | | '''6.25 μM''' | ||
+ | | '''3.12 μM''' | ||
+ | | '''1.25 μM''' | ||
+ | | '''0.62 μM''' | ||
+ | | '''0.3 μM''' | ||
+ | | '''0 μM''' | ||
+ | |- | ||
+ | | '''TR Yellow''' | ||
+ | |- | ||
+ | | FK141 | ||
+ | | 44.02929134 | ||
+ | | 45.55669291 | ||
+ | | 45.04755906 | ||
+ | | 45.55669291 | ||
+ | | 43.52015748 | ||
+ | | 44.02929134 | ||
+ | | 45.55669291 | ||
+ | | 44.02929134 | ||
+ | | 44.5384252 | ||
+ | |- | ||
+ | | FK502 | ||
+ | | 46.06582677 | ||
+ | | 45.55669291 | ||
+ | | 45.04755906 | ||
+ | | 43.52015748 | ||
+ | | 44.02929134 | ||
+ | | 45.55669291 | ||
+ | | 45.04755906 | ||
+ | | 46.06582677 | ||
+ | | 46.57496063 | ||
+ | |- | ||
+ | | '''TR Green''' | ||
+ | |- | ||
+ | | FK296 | ||
+ | | 44.01818898 | ||
+ | | 45.54488189 | ||
+ | | 45.54488189 | ||
+ | | 45.54488189 | ||
+ | | 46.567717 | ||
+ | | 46.05377953 | ||
+ | | 45.54488189 | ||
+ | | 46.05377953 | ||
+ | | 46.56267717 | ||
+ | |- | ||
+ | | FK502 | ||
+ | | 46.05 | ||
+ | | 46.05 | ||
+ | | 43.51 | ||
+ | | 43.51 | ||
+ | | 43.00 | ||
+ | | 43.00 | ||
+ | | 43.51 | ||
+ | | 43.51 | ||
+ | | 43.51 | ||
+ | |- | ||
+ | | '''TR Blue''' | ||
+ | |- | ||
+ | | FK141 | ||
+ | | 38.93 | ||
+ | | 44.538 | ||
+ | | 45.047 | ||
+ | | 46.065 | ||
+ | | 46.575 | ||
+ | | 47.593 | ||
+ | | 46.574 | ||
+ | | 46.574 | ||
+ | | 46.066 | ||
+ | |- | ||
+ | | FK189 | ||
+ | | 46.574 | ||
+ | | 47.084 | ||
+ | | 46.574 | ||
+ | | 46.574 | ||
+ | | 46.574 | ||
+ | | 46.066 | ||
+ | | 45.557 | ||
+ | | 42.502 | ||
+ | | 42.501 | ||
+ | |- | ||
+ | | '''TR Purple''' | ||
+ | |- | ||
+ | | FK189 | ||
+ | | 45.05 | ||
+ | | 44.54 | ||
+ | | 45.05 | ||
+ | | 44.54 | ||
+ | | 44.54 | ||
+ | | 44.03 | ||
+ | | 40.47 | ||
+ | | 43.01 | ||
+ | | 45.05 | ||
+ | |- | ||
+ | | FK502 | ||
+ | | 45.56 | ||
+ | | 44.54 | ||
+ | | 45.56 | ||
+ | | 45.05 | ||
+ | | 46.57 | ||
+ | | 43.52 | ||
+ | | 44.54 | ||
+ | | 46.07 | ||
+ | | 45.56 | ||
+ | |- | ||
+ | | '''WF Green''' | ||
+ | |- | ||
+ | | FK189 | ||
+ | | 47.580 | ||
+ | | 47.580 | ||
+ | | 47.072 | ||
+ | | 46.563 | ||
+ | | 46.563 | ||
+ | | 47.072 | ||
+ | | 48.089 | ||
+ | | 48.089 | ||
+ | | 47.580 | ||
+ | |- | ||
+ | | FK296 | ||
+ | | 44.018 | ||
+ | | 42.491 | ||
+ | | 47.580 | ||
+ | | 47.580 | ||
+ | | 47.072 | ||
+ | | 47.580 | ||
+ | | 49.616 | ||
+ | | 49.616 | ||
+ | | 50.634 | ||
+ | |- | ||
+ | | '''WF Blue''' | ||
+ | |- | ||
+ | | FK141 | ||
+ | | 46.09 | ||
+ | | 46.09 | ||
+ | | 46.60 | ||
+ | | 47.11 | ||
+ | | 40.00 | ||
+ | | 47.11 | ||
+ | | 47.11 | ||
+ | | 47.11 | ||
+ | | 47.11 | ||
+ | |- | ||
+ | | FK296 | ||
+ | | 45.08 | ||
+ | | 43.55 | ||
+ | | 47.11 | ||
+ | | 43.04 | ||
+ | | 47.11 | ||
+ | | 47.11 | ||
+ | | 57.26 | ||
+ | | 57.26 | ||
+ | | 42.54 | ||
+ | |- | ||
+ | |} | ||
+ | </center> | ||
==Module 2: Protein engineering== | ==Module 2: Protein engineering== | ||
Please find uploaded data for Mod 2 in the Dropbox folder linked [[ here]]. | Please find uploaded data for Mod 2 in the Dropbox folder linked [[ here]]. |
Revision as of 19:01, 29 February 2024
Module 1: Drug discovery
Please find uploaded data for Mod 1 in the Dropbox folder linked [here].
Please find the SMM screen results here.
DSF results:
DMSO | Small molecule | 12.5 μM | 6.25 μM | 3.12 μM | 1.25 μM | 0.62 μM | 0.3 μM | 0 μM | |
TR Yellow | |||||||||
FK141 | 44.02929134 | 45.55669291 | 45.04755906 | 45.55669291 | 43.52015748 | 44.02929134 | 45.55669291 | 44.02929134 | 44.5384252 |
FK502 | 46.06582677 | 45.55669291 | 45.04755906 | 43.52015748 | 44.02929134 | 45.55669291 | 45.04755906 | 46.06582677 | 46.57496063 |
TR Green | |||||||||
FK296 | 44.01818898 | 45.54488189 | 45.54488189 | 45.54488189 | 46.567717 | 46.05377953 | 45.54488189 | 46.05377953 | 46.56267717 |
FK502 | 46.05 | 46.05 | 43.51 | 43.51 | 43.00 | 43.00 | 43.51 | 43.51 | 43.51 |
TR Blue | |||||||||
FK141 | 38.93 | 44.538 | 45.047 | 46.065 | 46.575 | 47.593 | 46.574 | 46.574 | 46.066 |
FK189 | 46.574 | 47.084 | 46.574 | 46.574 | 46.574 | 46.066 | 45.557 | 42.502 | 42.501 |
TR Purple | |||||||||
FK189 | 45.05 | 44.54 | 45.05 | 44.54 | 44.54 | 44.03 | 40.47 | 43.01 | 45.05 |
FK502 | 45.56 | 44.54 | 45.56 | 45.05 | 46.57 | 43.52 | 44.54 | 46.07 | 45.56 |
WF Green | |||||||||
FK189 | 47.580 | 47.580 | 47.072 | 46.563 | 46.563 | 47.072 | 48.089 | 48.089 | 47.580 |
FK296 | 44.018 | 42.491 | 47.580 | 47.580 | 47.072 | 47.580 | 49.616 | 49.616 | 50.634 |
WF Blue | |||||||||
FK141 | 46.09 | 46.09 | 46.60 | 47.11 | 40.00 | 47.11 | 47.11 | 47.11 | 47.11 |
FK296 | 45.08 | 43.55 | 47.11 | 43.04 | 47.11 | 47.11 | 57.26 | 57.26 | 42.54 |