Difference between revisions of "20.109(S24):Class data"
From Course Wiki
(→Module 1: Drug discovery) |
(→Module 1: Drug discovery) |
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Line 154: | Line 154: | ||
|- | |- | ||
| DMSO | | DMSO | ||
− | | 47. | + | | 47.11 |
− | | 66. | + | | 66.92 |
− | | 81. | + | | 81.65 |
− | | 65. | + | | 65.23 |
|- | |- | ||
| Small molecule #1 | | Small molecule #1 | ||
− | | 36. | + | | 36.44 |
− | | 65. | + | | 65.91 |
− | | 66. | + | | 66.41 |
− | | 56. | + | | 56.25 |
|- | |- | ||
| Small molecule #2 | | Small molecule #2 | ||
− | | 45. | + | | 45.59 |
− | | 82. | + | | 82.67 |
− | | 47. | + | | 47.62 |
− | | 58. | + | | 58.63 |
|- | |- | ||
| Small molecule #10 | | Small molecule #10 | ||
− | | 47. | + | | 47.11 |
− | | 84. | + | | 84.19 |
− | | 82. | + | | 82.16 |
− | | 71. | + | | 71.15 |
|- | |- | ||
| Small molecule #11 | | Small molecule #11 | ||
− | | 45. | + | | 45.08 |
− | | 82. | + | | 82.16 |
− | | 81. | + | | 81.65 |
− | | 69. | + | | 69.63 |
|- | |- | ||
|} | |} |
Revision as of 21:47, 29 February 2024
Module 1: Drug discovery
Please find uploaded data for Mod 1 in the Dropbox folder linked here.
Please find the SMM screen results here.
DSF results:
Replicate #1 | Replicate #2 | Replicate #3 | Average Tm | |
TR Orange | ||||
DMSO | ||||
Small molecule #1 | ||||
Small molecule #6 | ||||
Small molecule #9 | ||||
Small molecule #10 | ||||
TR Yellow | ||||
DMSO | 48.12 | 47.61 | 49.13 | 48.29 |
Small molecule #2 | 48.62 | 46.59 | 44.55 | 46.59 |
Small molecule #10 | 47.61 | 47.61 | 47.61 | 47.61 |
Small molecule #11 | 44.5 | 45.6 | 44.5 | 44.9 |
Small molecule #13 | 47.1 | 47.1 | 49.1 | 47.8 |
TR Green | ||||
DMSO | 43.02 | 45.06 | 45.06 | 44.37 |
Small molecule #2 | 43.02 | 47.10 | 45.57 | 45.23 |
Small molecule #6 | 46.08 | 49.65 | 46.08 | 47.27 |
Small molecule #9 | 44.04 | 45.06 | 46.59 | 45.23 |
Small molecule #10 | 46.08 | 45.57 | 48.62 | 46.76 |
TR Blue | ||||
DMSO | 47.11149606 | 45.07968504 | 44.06377953 | 45.41832021 |
Small molecule #1 | 48.63535433 | 48.63535433 | 44.06377953 | 47.11149606 |
Small molecule #2 | 46.60354331 | 47.11149606 | 43.55582677 | 45.75695538 |
Small molecule #4 | 46.60354331 | 44.57173228 | 43.55582677 | 44.91036745 |
Small molecule #10 | 47.61944882 | 44.57173228 | 44.06377953 | 45.41832021 |
TR Pink | ||||
DMSO | 47.11 | 66.92 | 81.65 | 65.23 |
Small molecule #1 | 36.44 | 65.91 | 66.41 | 56.25 |
Small molecule #2 | 45.59 | 82.67 | 47.62 | 58.63 |
Small molecule #10 | 47.11 | 84.19 | 82.16 | 71.15 |
Small molecule #11 | 45.08 | 82.16 | 81.65 | 69.63 |
Replicate #1 | Replicate #2 | Replicate #3 | Average Tm | |
WF Red | ||||
DMSO | ||||
Small molecule #3 | ||||
Small molecule #4 | ||||
Small molecule #5 | ||||
Small molecule #8 | ||||
WF Orange | ||||
DMSO | ||||
Small molecule #1 | ||||
Small molecule #2 | ||||
Small molecule #10 | ||||
Small molecule #13 | ||||
WF Yellow | ||||
DMSO | ||||
Small molecule #2 | ||||
Small molecule #10 | ||||
Small molecule #11 | ||||
Small molecule #13 | ||||
WF Green | ||||
DMSO | ||||
Small molecule #2 | ||||
Small molecule #9 | ||||
Small molecule #10 | ||||
Small molecule #13 | ||||
WF Blue | ||||
DMSO | ||||
Small molecule #5 | ||||
Small molecule #9 | ||||
Small molecule #10 | ||||
Small molecule #13 | ||||
WF Pink | ||||
DMSO | ||||
Small molecule #5 | ||||
Small molecule #9 | ||||
Small molecule #10 | ||||
Small molecule #13 | ||||
WF Purple | ||||
DMSO | ||||
Small molecule #5 | ||||
Small molecule #9 | ||||
Small molecule #10 | ||||
Small molecule #13 | ||||
WF Teal | ||||
DMSO | ||||
Small molecule #1 | ||||
Small molecule #2 | ||||
Small molecule #10 | ||||
Small molecule #11 |